Jin Lab

We study gene regulation, chromatin organization, and single-cell genomics to understand how regulatory programs shape cellular function and disease.

Research

Enhancer, promoter, and transcription-factor programs that establish cell identity and response.

Chromatin states, histone marks, and regulatory annotations across development and disease contexts.

Genome folding, long-range contacts, and spatial regulatory mechanisms measured with chromosome conformation assays.

Cell-state heterogeneity and lineage dynamics resolved with single-cell and multi-omic measurements.

Algorithms, benchmarking, and reproducible resources for interpreting high-dimensional genomic data.

Youngrok Park, Wanying Xu, Tianyi Yang, Victoria Hill, Xiaoyuan He, Lisa Sadzewicz, Luke Tallon, Jung-Sik Kim, ..., Fulai Jin, et al.

PLOS One · DOI: 10.1371/journal.pone.0333128 · PMID: 41091719

Dylan Plummer, Xiuyuan Lang, Shanshan Zhang, Yan Li, Jing Li, Fulai Jin

Nature Communications · DOI: 10.1038/s41467-025-64186-4 · PMID: 41087414

Dongbing Lai, Michael Zhang, Nick Green, Marco Abreu, Tae-Hwi Schwantes-An, Clarissa C. Parker, Shanshan Zhang, Fulai Jin, et al.

Molecular Psychiatry · DOI: 10.1038/s41380-025-03294-5 · PMID: 41057643

A Public Resource for Pancreatic Beta Cell

Regressing Principle components for the Assembly of Continuous Trajectory

A Hi-C Data Bias-Correction Pipeline

Jin Lab is actively seeking motivated students and postdocs with experimental and/or computational experience.